DNA Isolation and Input Preparation
Optional DNA isolation from compatible research specimens before library preparation, with project-specific input review and quality-control planning.
Sequencing-Ready Libraries
NGS Library Preparation Services
Sequencing-ready library preparation with optional DNA isolation and quality-control support for customer projects and multiple sample types.
We support DNA isolation from compatible research specimens when needed, followed by DNA and RNA library preparation, amplicon and target-enrichment workflows, indexing and multiplexing, library quantification and quality assessment, and customer-supplied library QC with sequencing support.
Submit purified nucleic acid directly for library preparation, or use the DNA Isolation Request when B&B Bio will isolate DNA from the submitted specimen before library preparation.
Library Preparation Capabilities
Flexible Support from Sample Input to Sequencing-Ready Library
Projects can begin with a compatible source specimen, purified DNA or RNA, or a customer-prepared library. We align DNA isolation, library strategy, target or amplicon design, indexing, quality control, and downstream sequencing to the requested workflow.
DNA and RNA Library Preparation
Project-specific preparation of DNA or RNA libraries for compatible next-generation sequencing workflows.
Amplicon and Target Enrichment
Library-preparation support for amplicon-based projects and targeted enrichment strategies.
Indexing and Multiplexing Support
Index planning and multiplexing support based on the project design, sample count, and sequencing workflow.
Library Quantification and Quality Assessment
Library concentration and quality assessment to support sequencing-readiness review.
Customer-Supplied Library QC and Sequencing Support
Quality-control review of customer-supplied libraries with project-specific sequencing support.
Supported Project Configurations
Library Preparation and QC for Multiple Project Types
Service scope can be aligned with source specimens requiring DNA isolation, purified DNA or RNA inputs, targeted or amplicon workflows, multiplexed studies, and customer-prepared libraries requiring QC or sequencing support.
DNA Sequencing Projects
Begin with purified DNA or request DNA isolation from a compatible submitted specimen before library preparation.
RNA Sequencing Projects
RNA library preparation planned around the project design, supplied material, and sequencing requirements.
Amplicon and Targeted Studies
Support for projects using defined amplicons or target-enrichment workflows.
Customer-Supplied Libraries
Quality assessment and sequencing support for libraries prepared by the customer.
From Sample or Nucleic Acid Input to Sequencing-Ready Libraries
The workflow is adjusted to whether DNA isolation is required, the supplied material, library method, indexing plan, quality-control requirements, and downstream sequencing needs.
Define the Project and Starting Material
Provide the source specimen or nucleic-acid input, requested DNA isolation if applicable, library strategy, sample count, target or amplicon details, and sequencing requirements.
Isolate DNA When Needed and Prepare Libraries
Perform the requested DNA isolation for compatible specimens when applicable, then prepare and index libraries using the agreed workflow.
Quantify and Assess Quality
Review library concentration and quality against the project-specific sequencing-readiness criteria.
Release or Support Sequencing
Provide sequencing-ready libraries and agreed QC documentation, or continue with project-specific sequencing support.
Need Help Choosing the Right Starting Point?
Contact B&B Bio if you are unsure whether to submit a DNA Isolation Request first or proceed directly with the NGS Library Preparation Request.
Research Use Only. DNA isolation, NGS library preparation, quality-control, and sequencing-support services are intended for research applications and are not for use in diagnostic procedures.