Microscope, DNA helix, cell-culture dishes, and molecular research materials in a laboratory

B&B Bio Research Services

Research Services

Customized molecular biology services supporting cell-line quality, plasmid engineering, research-grade RNA production, and precise genome editing in human cell-line models.

Each project is reviewed for technical feasibility, starting material, experimental objectives, quality controls, timeline, and required deliverables before laboratory work begins.

Discuss a Research Project

Research Service Areas

Cell-Line Authentication Services

We provide human cell-line authentication using short tandem repeat (STR) profiling to confirm cell-line identity, detect cross-contamination, and support reliable, reproducible research. Services may also include mycoplasma testing, comparison with reference profiles, and a clear results report for research documentation and quality-control purposes.

  • Human STR profiling
  • Comparison with available reference profiles
  • Cross-contamination and identity review
  • Optional mycoplasma testing
  • Clear, research-focused results reporting
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Plasmid Services

Our plasmid services support custom vector design and construction for research applications, including gene synthesis, subcloning, site-directed mutagenesis, promoter or tag modification, plasmid amplification, purification, and sequence verification. We provide customized plasmid solutions for gene-expression studies, reporter assays, genome-editing projects, and human cell-line model development.

  • Custom vector design and gene synthesis
  • Subcloning and site-directed mutagenesis
  • Promoter, tag, and insert modification
  • Plasmid amplification and purification
  • Sequence verification and project documentation
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In Vitro Transcription Services

We provide customized in vitro transcription services to produce research-grade RNA from plasmid or synthetic DNA templates. Services may include template preparation, RNA synthesis, purification, concentration and integrity assessment, and optional capping or polyadenylation for applications in gene-expression studies, genome editing, assay development, and human cell-line research.

  • Plasmid or synthetic DNA template preparation
  • Research-grade RNA synthesis and purification
  • RNA concentration and integrity assessment
  • Optional capping and polyadenylation
  • Customized project scale and deliverables
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Genome Editing (CRISPR/Cas)

CRISPR/Cas genome editing enables precise DNA modification in human cell-line models, including gene knockout, gene knock-in, gene correction, and targeted sequence changes. We offer customized editing-strategy design, guide RNA development, clone isolation, and molecular validation to support functional genomics, disease modeling, drug-target validation, and preclinical research.

  • Editing-strategy and guide RNA design
  • Gene knockout and gene knock-in
  • Gene correction and targeted sequence changes
  • Single-clone isolation and screening
  • Molecular confirmation of edited cell lines
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Project Workflow

  1. Discuss the Project

    We review the research objective, starting material, requested service, technical constraints, and expected output.

  2. Define the Scope

    The agreed scope defines methods, sample requirements, quality controls, milestones, estimated timeline, and deliverables.

  3. Execute the Work

    Laboratory activities are performed using controlled procedures and project-specific acceptance criteria.

  4. Receive Results

    Results, materials, and supporting documentation are delivered according to the approved project plan.

Project-Specific Scope

Services are tailored to the research question, biological material, and requested output.

Technical Communication

Direct discussion of feasibility, requirements, progress, limitations, and deliverables.

Documented Results

Clear project records and reports appropriate to the agreed research-service scope.

Confidential Handling

Project information and submitted materials are handled according to agreed requirements.

Typical Research Applications

Cell-Line Quality Control

Authentication and mycoplasma-testing support for cell lines used in research, manufacturing development, and publication.

Gene-Expression Studies

Custom plasmids and research-grade RNA for expression analysis, reporter assays, and assay-development workflows.

Human Cell-Line Models

Engineered cell models for disease mechanisms, target validation, functional studies, and preclinical research.

Functional Genomics

Gene knockout, knock-in, correction, and targeted modification projects for mechanistic research.

Plan Your Research Project

Contact B&B Bio to discuss feasibility, sample requirements, project scope, timeline, quality controls, and deliverables.

Request a Consultation

B&B Bio research services are intended for research use only and are not intended for diagnostic procedures unless separately validated and authorized under applicable regulations. Final project scope, acceptance criteria, timeline, and deliverables are established before work begins.