DNA sequencing and genomic data visualization

B&B Bio Sequencing Services

Next Generation Sequencing

Integrated sequencing support for genomic, transcriptomic, oncology, liquid-biopsy, microbiome, and custom library-preparation projects.

Each project is reviewed for sample type, sequencing strategy, coverage requirements, library workflow, bioinformatics needs, timeline, and deliverables before work begins.

Discuss an NGS Project

Next Generation Sequencing Services

Whole Exome Sequencing

Sequencing of protein-coding regions to support variant discovery and genomic research.

  • Genomic DNA input review
  • Exome capture and library preparation
  • Sequencing and read-quality assessment
  • SNV and small-indel analysis options
  • FASTQ, BAM, and VCF deliverables
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Transcriptome Sequencing

RNA-sequencing support for gene-expression, transcript, fusion, and pathway-focused research.

  • RNA quality and quantity review
  • mRNA or total-RNA workflows
  • Differential-expression analysis options
  • Transcript and fusion analysis support
  • Sequencing data and analysis reports
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Precision Oncology Focused Panels (AmpliSeq)

Targeted sequencing panels for focused cancer-research, biomarker, and human cell-line model projects.

  • Predefined or project-specific panels
  • FFPE-compatible workflow options
  • Focused high-depth sequencing
  • Variant-analysis support
  • Research-focused data interpretation
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Liquid Biopsy

Sequencing support for circulating cell-free nucleic-acid research using plasma and other suitable materials.

  • Plasma and cfDNA input review
  • Low-input library workflows
  • Focused panel sequencing options
  • High-depth variant analysis
  • Longitudinal research-study support
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Microbiome

Microbiota 16S rRNA Gene Sequencing

Targeted microbial-community profiling for diversity, composition, and comparative research.

  • 16S amplicon library preparation
  • Microbial diversity assessment
  • Taxonomic abundance profiling

Bacterial Whole Genome Sequencing

Whole-genome sequencing of bacterial isolates for strain-level and genomic characterization.

  • Bacterial DNA input review
  • Genome assembly options
  • Species, strain, resistance, and virulence analysis options
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DNA Isolation & NGS Library Preparation Services

Sequencing-ready library preparation and quality-control support for customer projects and multiple sample types.

  • DNA isolation
  • DNA and RNA library preparation
  • Amplicon and target-enrichment workflows
  • Indexing and multiplexing support
  • Library quantification and quality assessment
  • Customer-supplied library QC and sequencing support
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Project Workflow

  1. Review the Project

    We review the research objective, sample type, sequencing application, coverage needs, library strategy, and requested output.

  2. Assess Samples and Libraries

    Input material and prepared libraries are assessed against project-specific quantity and quality requirements.

  3. Prepare Libraries and Sequence

    Libraries are prepared or accepted, indexed, pooled, and sequenced using the agreed run configuration and controls.

  4. Deliver Data

    Raw data, processed files, quality summaries, and optional bioinformatics reports are delivered as defined.

Flexible Scope

Projects are configured around the research objective, input material, depth, and deliverables.

Quality Review

Sample, library, and sequencing quality are reviewed at defined workflow stages.

Bioinformatics Options

Data delivery can include raw files, processed outputs, and project-specific analysis.

Confidential Handling

Research materials, project information, and data are handled according to agreed requirements.

Typical Research Applications

Genomic Variant Research

Exome-based projects focused on coding variants, inherited conditions, population studies, and model systems.

Gene-Expression Studies

Transcriptome analysis for differential expression, pathway research, biomarker discovery, and treatment-response studies.

Oncology Research

Focused tumor, human cell-line, and liquid-biopsy projects using targeted panels and high-depth sequencing strategies.

Microbial Genomics

Microbiota profiling and bacterial whole-genome sequencing for community and isolate characterization.

Plan Your Sequencing Project

Contact B&B Bio to discuss sample requirements, library preparation, sequencing strategy, bioinformatics, timeline, and deliverables.

Request a Consultation

B&B Bio next generation sequencing services are intended for research use only and are not intended for diagnostic procedures unless separately validated and authorized under applicable regulations. Final project scope, sample acceptance criteria, sequencing specifications, timeline, and deliverables are established before work begins.